libera/##covid-19/ Monday, 2024-10-21

BrainstormNew from MedPageToday: Preeclampsia Flagged by Common Lab Values: (MedPage Today) -- PHILADELPHIA  --  Existing blood tests may help identify pregnant women at risk of developing preeclampsia, researchers found from a retrospective chart review.Calculated from lab values taken at admission for labor, the fibrinogen... → https://www.medpagetoday.com/meetingcoverage/asa/11248800:22
BrainstormNew from Marc Veldhoen on Mastodon: (news): The difference between SARS-Cov-2 and other infections was an adult population without immune memory. → https://mastodon.online/@marc_veld/11334225634330158701:10
BrainstormNew from Politico: The future is bright for beer – given the right policy framework: Beer plays an important role in Europe’s economy, but excise burdens, production costs and the post-Covid environment are putting pressure on the sector’s ability to act as a [... want %more?] → https://www.politico.eu/sponsored-content/the-future-is-bright-for-beer-given-the-right-policy-framework/05:13
BrainstormNew from r/COVID19: COVID19: Efficacy of Air Cleaning Units for preventing SARS-CoV-2 and other hospital-acquired infections on medicine for older people wards: A quasi-experimental controlled before-and- after study → https://old.reddit.com/r/COVID19/comments/1g8irmj/efficacy_of_air_cleaning_units_for_preventing/07:56
BrainstormNew from Science-Based Medicine: “And we’d better not risk another frontal assault. That plasmid’s dynamite.” Antivaxxers vs. plasmid DNA: Ever since recombinant DNA has been used to develop and manufacture vaccines, antivaxxers have [... want %more?] → https://sciencebasedmedicine.org/and-wed-better-not-risk-another-frontal-assault-that-plasmids-dynamite-antivaxxers-vs-plasmid-dna/09:04
BrainstormNew from StatNews: STAT+: Perplexing results from Duchenne muscular dystrophy trial raise questions about gene therapies: A Pfizer result is unsettling the gene therapy push for Duchenne muscular dystrophy: The boys didn't improve even though a biomarker target was achieved. → https://www.statnews.com/2024/10/21/duchenne-muscular-dystrophy-gene-therapy-pfizer-sarepta/10:33
BrainstormNew from Marc Veldhoen on Mastodon: (news): A persistent neutrophil-associated immune signature characterizes post–COVID-19 pulmonary sequelae → https://mastodon.online/@marc_veld/11334462857574613511:13
BrainstormNew from BioNTech: BioNTech to Report Third Quarter 2024 Financial Results and Corporate Update on November 4, 2024: MAINZ, Germany, October 21, 2024 (GLOBE NEWSWIRE) --  BioNTech SE (Nasdaq: BNTX, “BioNTech” or “the Company”) will announce [... want %more?] → https://investors.biontech.de/news-releases/news-release-details/biontech-report-third-quarter-2024-financial-results-and12:52
pepe420how bout them vaccines?12:58
BrainstormNew from Reddit (test): COVID19_Pandemic: Laura Miers: "Four causes of human H5N1 have been reported in Washington. California just reported 13 human H5N1 cases in two weeks, & 6 Missouri healthcare workers got sick from a single H5N1 patient who had no contact with [... want %more?] → https://old.reddit.com/r/COVID19_Pandemic/comments/1g8npyd/laura_miers_four_causes_of_human_h5n1_have_been/13:51
BrainstormNew from Reddit (test): COVID19_Pandemic: [June 2024, Norway] Flere unge døde av sykdom: Forskere slår alarm/More young people died of disease: Researchers sound the alarm [“Disease took an unusually high number of young lives last year. Researchers fear that late [... want %more?] → https://old.reddit.com/r/COVID19_Pandemic/comments/1g8nr76/june_2024_norway_flere_unge_døde_av_sykdom/14:10
BrainstormNew from StatNews: The biotech updates you need to read this morning: Pfizer suffered a blow earlier this month when new data showed that its gene therapy for Duchenne muscular dystrophy failed to help participants demonstrate significant improvement in [... want %more?] → https://www.statnews.com/2024/10/21/biotech-news-catalent-novo-nordisk-seaport-pfizer-duchenne-340b-drug-the-readout/14:50
BrainstormNew from r/COVID19: COVID19: Trends in Pediatric Hospital Admissions Caused or Contributed by SARS-CoV-2 Infection in England → https://old.reddit.com/r/COVID19/comments/1g8pmmk/trends_in_pediatric_hospital_admissions_caused_or/15:30
BrainstormNew from Contagion Live: Pfizer’s RSVpreF Vaccine Shows Efficacy in High-Risk Adults Aged 18-59: Study results show that the vaccine elicits a comparable immune response in high-risk adults aged 18-59 with chronic medical conditions, suggesting potential for broader [... want %more?] → https://www.contagionlive.com/view/pfizer-s-rsvpref-vaccine-shows-efficacy-in-high-risk-adults-aged-18-5915:50
BrainstormNew from BMJ: Half of UK workers don’t have access to essential workplace healthcare, report finds: Over 10 million people in the UK, or around half the workforce, don’t have access to essential health support through their work, such as routine health checks or influenza vaccinations, the Royal Society for Public Health [... want %more?] → http://www.bmj.com/content/387/bmj.q2317.short17:34
ublx%more17:38
Brainstormublx, [...] has found.1In a report published on 21 October, it said that the current workplace health system was widening health inequalities, with workers in lower paid industries such as agriculture and hospitality most likely to miss out on support. The poor provision of workplace healthcare was also adding to pressure on the health service, it said.“It cannot [...] → https://paste.ee/p/WChXX17:38
ublxseems suspiciously like part of clandestine efforts to shift healthcare access from NHS to employer-mediated provision, which ofc we can partly suspect has more to do with workforce politics (employee discipline) than healthcare18:14
BrainstormNew from Marc Veldhoen on Mastodon: (news): There is no evidence for this and is in stark contrast to the studies clearly showing protective effects from immune memory and better innate immunity in children. For a more scientific estimate, I refer to @GidMK ´s substack; https:// gidmk.substack.com/p/how-many- children-get-long-covid → https://mastodon.online/@marc_veld/11334651210652364719:15
LjLublx, hey21:22
LjLwhat are you saying is part of such effort, the article?21:23
ublxyeah more or less21:30
ublxwith a suspicious mind, one sees seeming efforts everywhere one looks, of a general campaign to convert UK healthcare to the US model21:31
ublxsome obvious, blatant. some less so like this21:31
LjLublx, a thing i caught yesterday https://www.reddit.com/r/science/comments/1g83iti/sarscov2specific_plasma_cells_are_not_durably/ doesn't sound like great news, but note the idea somewhere in that thread that this only happens with the vaccines and not the disease seems a bit bogus since everyone in this study had the vaccine23:01
LjLthen this comment https://www.reddit.com/r/science/comments/1g83iti/sarscov2specific_plasma_cells_are_not_durably/lsz3ovk/ shows a similar-seeming study on people who got the disease and not necessarily the vaccine23:01
LjLso maybe there is just no long-lasting immunity which is \o/23:02
ublxfor me growing up, the household wisdom or science orthodoxy back then was that one just can't have general immunity from coronaviruses (neither via vaccine nor infection). so i suppose people of my age, when back in 2020 there was all this talk of warp speed vaccine development, well a lot of people my age must have been thinking.. what in the heck is this nonsense about vaccine23:06
LjLi can't say i had any household wisdom about coronaviruses :P23:14
ublxsomething something mutate too fast for meaningful immunity to ever emerge as an option. probably discussed in high school biology level, i can't remember. but i do remember this general idea about cold/coronaviruses being the received wisdom back when i was a kid23:16
ublxofc the vaccines we did get post-2020 were not nothing. and ofc things should be tried23:16
ublxbut an actual, broadly effective, lasting immunity with respect to coronaviruses.. well i grew up thinking that would be a star trek level science state of the art paradigm shift23:18
ublxso i took the vaccines, and boosters (for a while anyway). but it didn't exactly blow my mind when they turned out to be weak sauce23:19
LjL2020-06-28.log:[21:19:37] <LjL> in my opinion we'll have a vaccine for western countries, it'll be effective for 6 months to 2 years, after which you'll need a booster, which will increase immunity, you may get 5-6 years with a booster, and the vaccine testing will continue for the next decade or two, until we have probably a 3-immunization sequence: initial, booster, second booster23:21
LjLah, the naivity23:21
LjLmore like 3 months to 6 months, *with* the booster23:21
ublxwell. better than nothing. surely saved a lot of lives23:24
ublxone fine day humanity will get some star trek level nanotech miracle vaccines23:24
ublx*one fine day in the quite distant future23:25
BrainstormNew from MedPageToday: How Do Younger People Fare With Stool Tests for CRC Screening?: (MedPage Today) -- When given the option, patients ages 45-49 completed colorectal cancer (CRC) screening via fecal immunochemical test (FIT) at about the same rate as 50-year-olds, according to a large retrospective cohort [... want %more?] → https://www.medpagetoday.com/gastroenterology/coloncancer/11249923:26

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