libera/##covid-19/ Thursday, 2024-05-16

BrainstormNew from r/COVID19: COVID19: SARS-CoV-2 recombinant spike ferritin nanoparticle vaccine adjuvanted with Army Liposome Formulation containing monophosphoryl lipid A and QS-21: a phase 1, randomised, double-blind, placebo-controlled, first-in-human clinical trial → https://old.reddit.com/r/COVID19/comments/1csy3yp/sarscov2_recombinant_spike_ferritin_nanoparticle/00:56
LjLwtf that "vision" thing01:53
BrainstormNew from r/COVID19: COVID19: Antibody Fingerprints Linking Adenoviral Anti-PF4 Disorders → https://old.reddit.com/r/COVID19/comments/1ct05rw/antibody_fingerprints_linking_adenoviral_antipf4/02:34
BrainstormNew from r/Coronavirus: Coronavirus: NC Senate votes to ban people from wearing masks in public for health reasons → https://old.reddit.com/r/Coronavirus/comments/1ct5ql2/nc_senate_votes_to_ban_people_from_wearing_masks/07:44
BrainstormNew from Marc Veldhoen on Mastodon: (news): A virus infection can result in high IFN levels. This can drive inhibitory responses to reduce the risk of damaging your own tissues. This can result in an increased risk of other infections. IFN with SARS-CoV-2 is not a large problem. → https://mastodon.online/@marc_veld/11244952505371257809:21
BrainstormNew from EMA: What's new: (news): Human medicines European public assessment report (EPAR): Zoonotic Influenza Vaccine Seqirus, Zoonotic influenza vaccine (H5N8) (surface antigen, inactivated, adjuvanted), Date of authorisation: 09/10/2023, Revision: 1, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/zoonotic-influenza-vaccine-seqirus11:10
BrainstormNew from EMA: What's new: (news): European Medicines Agency's data protection notice on the study of the “Natural history of coagulopathy in COVID-19 patients and persons vaccinated against SARS-CoV- during the Omicron period” → https://www.ema.europa.eu/system/files/documents/other/ema-tda-011-dpn-hdh-study_history-coagulopathy_en.pdf11:30
BrainstormNew from BBC Health: HPV vaccine stops 90% of cervical cancer cases: England began vaccinating teenage girls in 2008 and results show it is paying off. → https://www.bbc.com/news/articles/cv2x2en4lpro12:09
BrainstormNew from r/Science: science: A small number of New York City wild birds carry highly pathogenic H5N1 avian influenza, according to a recent study. The potential for zoonotic infections or even pandemics may not be limited to rural environments and commercial poultry [... want %more?] → https://old.reddit.com/r/science/comments/1ct9sx9/a_small_number_of_new_york_city_wild_birds_carry/12:48
BrainstormNew from Johnson&Johnson: Johnson & Johnson to Acquire Proteologix, Inc. to Lead in Atopic Dermatitis Treatment: Acquisition advances Johnson & Johnson’s leading Dermatology portfolio with opportunity to address significant unmet need in [... want %more?] → https://www.jnj.com/media-center/press-releases/johnson-johnson-to-acquire-proteologix-inc-to-lead-in-atopic-dermatitis-treatment13:42
BrainstormNew from StatNews: Blackstone wants in on red-hot immunology market: Blackstone Life Sciences said it's committing up to $300 million to launch a new immunology and inflammation-focused company called Uniquity Bio. Uniquity will start Phase 2 trials for solrikitug, [... want %more?] → https://www.statnews.com/2024/05/16/biotech-news-biogen-ionis-johnson-novartis-roche-blackstone-galapagos/14:21
BrainstormNew from Reddit (test): CoronavirusUK: Honesty About Covid is Essential for Progress → https://old.reddit.com/r/CoronavirusUK/comments/1ctcy5d/honesty_about_covid_is_essential_for_progress/15:42
BrainstormNew from MedPageToday: Slovakian PM's Prognosis; Kate Middleton's Treatment; Drug Test Cheating: (MedPage Today) -- Note that some links may require registration or subscription.Slovakian Prime Minister Robert Fico was shot multiple times and gravely wounded, but is expected to survive. [... want %more?] → https://www.medpagetoday.com/publichealthpolicy/washington-watch/11015016:21
BrainstormNew from Reddit (test): CoronavirusUK: SUPERNOVA Phase III trial of sipavibart long-acting antibody met primary endpoints in preventing COVID-19 in immunocompromised patient population → https://old.reddit.com/r/CoronavirusUK/comments/1cteoot/supernova_phase_iii_trial_of_sipavibart/16:51
BrainstormNew from MedPageToday: HPV Vaccination Program in England Was Effective Across Socioeconomic Groups: (MedPage Today) -- England's human papillomavirus (HPV) vaccination program has remained highly effective in reducing cases of cervical cancer and grade 3 cervical intraepithelial neoplasia (CIN3) across [... want %more?] → https://www.medpagetoday.com/infectiousdisease/stds/11015218:12
BrainstormNew from Eric Topol on Mastodon: (news): "SARS-CoV-2 infection should be considered as a risk factor for Alzheimer’s disease, even though the distinction between causation versus disease acceleration is not clear. “ → https://mstdn.social/@erictopol/11245191904050729619:32
BrainstormNew from Marc Veldhoen on Mastodon: (news): Also for respiratory infection, T cell functions may contain and resolve infection rather than completely prevent infection and early illness. This requires vaccine effectiveness to be assessed based on preventing severe disease and death rather than symptomatic infection. → https://mastodon.online/@marc_veld/11245210343379432720:12
ublxfrom the Stupidest Timeline™ - https://www.statnews.com/2024/05/15/bird-flu-raw-milk-fda-loophole-lax-enforcement-interstate-ban/20:19
LjLublx, would it make a huge difference if this were disallowed? aiui it'd only prevent transporting "across state lines"20:23
LjLalso i think it's unwise to rely on people following regulations, crossing fingers and hope they don't drink raw milk just because they aren't supposed to20:23
LjLalthough i don't know what the wise thing to do here is20:24
ublxguy running raw milk bootleg operation says 'H5N1 is "not real"'20:27
ublxstill belongs in stupidest timeline20:27
ublxalso, "More than 2,600 people were sickened and 228 hospitalized from drinking raw milk between 1998 and 2018, according to data from the Centers for Disease Control and Prevention."20:28
ublxwho the fuck drinks raw milk, knowing what we know about the health of cows in modern industrial dairy farms20:28
LjLublx, according to the FDA, who the fuck should eat cheese made from raw milk, either20:29
LjLand yet... that's pretty much every French person and a ton of Italians20:29
LjL(and more, i'm sure)20:29
ublxprobably the italians and french are not getting their milk from american industrial dairy farms20:30
LjLi doubt most farms are considerably better here...20:30
ublxwhere the cows are known to be made up of 1 part moo, 2 parts ulcerated udders, and 3 parts antibiotics20:30
BrainstormNew from WebMD: Get the Care You Need in a COVID-19 World: What to expect at the doctor’s office, hospitals, and long-term care facilities, the future of telemedicine, and how to get the best care during COVID-19. → https://www.webmd.com/healthy-aging/features/covid-senior-health-care20:31
ublxalso from the article: "That lapse in enforcement has taken on new significance as the H5N1 bird flu virus has spread to at least 46 dairy cow herds in nine states."20:31
ublx"has spread to at least 46 dairy cow herds in nine states."20:32
LjLto be clear, i don't drink raw milk at the best of times and i'd find now the worst time to start20:32
LjLbut at the same time, aside from the current threat, 2600 sick people in 30 years doesn't strike me as dramatic20:32
ublxi'll take "What is a gross understatement for £200 please, Alex"20:32
ublxhopefully (and perhaps plausibly) most folks drinking raw milk are getting it from low production intensity farms20:33
ublxdid you see the thing i linked the other day about discovery human flu receptors being widely expressed in cow udders?20:38
ublxbiorxiv, but still. https://www.biorxiv.org/content/10.1101/2024.05.03.592326v120:40
LjLublx, yeah, i did20:45
LjLnot great20:45
BrainstormNew from CIDRAP: COVID, other misinformation varies by topic, country on social media: The United Kingdom maintained a relatively stable proportion between questionable and reliable retweets. → https://www.cidrap.umn.edu/covid-19/covid-other-misinformation-varies-topic-country-social-media22:00
LjL<CarlSagan> [Ars Technica - Science] It could soon be illegal to publicly wear a mask for health reasons in NC https://arstechnica.com/?p=2025011 2024-05-16T19:25:2122:01
LjLwhat the *utter* fuck22:01
LjLof course, ancient laws against the KKK should stop health-related mask wearing...22:02
LjLhumans are idiots22:02
LjLhopeless idiots22:02
LjLtoday this is mandatory, tomorrow it's forbidden22:05
LjLno middle ground22:05
BrainstormNew from CIDRAP: COVID-19 linked to increased preterm birth, other problems in pregnancy: SARS-CoV-2 infection is tied to increased preterm birth (PTB), high blood pressure during pregnancy, and severe maternal morbidity. → https://www.cidrap.umn.edu/covid-19/covid-19-linked-increased-preterm-birth-other-problems-pregnancy22:19
BrainstormNew from CIDRAP: (news): Quick takes: Cholera vaccine shortages, pre-exposure COVID prevention, HPV screening specimen self-collection → https://www.cidrap.umn.edu/cholera/quick-takes-cholera-vaccine-shortages-pre-exposure-covid-prevention-hpv-screening-specimen22:43
BrainstormNew from MedPageToday: Texas Team's Wastewater Surveillance Can Pick Up Concerning H5N1 Mutations: (MedPage Today) -- While the CDC's recently launched wastewater dashboard reports levels of influenza A, a team in Texas is getting far more granular in its wastewater monitoring.The team at the Texas Epidemic [... want %more?] → https://www.medpagetoday.com/special-reports/exclusives/11016923:22
BrainstormNew from Contagion Live: Mortality is 35% Higher for COVID-19 Hospitalized Patients Compared to Influenza Inpatients: A new study demonstrates that for last year’s respiratory season, the difference in death rates are still much higher for [... want %more?] → https://www.contagionlive.com/view/mortality-is-35-higher-for-covid-19-hospitalized-patients-compared-to-influenza-inpatients23:42

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