| Brainstorm | New from Marc Veldhoen on Mastodon: (news): Much of Oz’s advice was bunk before the pandemic, it is bunk now, and there is no reason to assume it won’t be bunk after.....it’s all but guaranteed he would bring pseudoscience to the table when crafting and voting on legislation that affects the health and welfare. → https://mastodon.online/@marc_veld/113518036541101133 | 01:13 |
|---|---|---|
| Brainstorm | New from Virology.ws: Trial By Error: My Letter to BMJ Seeking Correction to Editorial on REGAIN Trial of Mental-and-Physical-Health Rehab for Long Covid: By David Tuller, DrPH I have recovered sufficiently from [... want %more?] → https://virology.ws/2024/11/20/trial-by-error-my-letter-to-bmj-seeking-correction-to-editorial-on-regain-trial-of-mental-and-physical-health-rehab-for-long-covid/ | 02:51 |
| Brainstorm | New from r/Science: science: Scientists have identified human antibodies that could prevent the malaria parasite from causing life-threatening infections → https://old.reddit.com/r/science/comments/1gw6ktq/scientists_have_identified_human_antibodies_that/ | 04:30 |
| Brainstorm | New from BMJ: Seven days in medicine: 13-19 November 2024: Pay disputeNorthern Ireland GPs are denied DDRB upliftDoctors in Northern Ireland have been told that they will not receive the 6% pay rise for 2024-25 recommended by the Doctors’ and Dentists’ Pay Review Body (DDRB), which has already been applied in the rest of [... want %more?] → http://www.bmj.com/content/387/bmj.q2559.short | 08:23 |
| Brainstorm | New from Marc Veldhoen on Mastodon: (news): Vaccines effectively eliminated some of the 20th century's most infectious diseases → https://mastodon.online/@marc_veld/113519770823406149 | 08:33 |
| Brainstorm | New from r/WorldNews: worldnews: US reopens Kyiv embassy after Ukraine firing of ATACMS missiles into Russia → https://old.reddit.com/r/worldnews/comments/1gwazi9/us_reopens_kyiv_embassy_after_ukraine_firing_of/ | 09:02 |
| Brainstorm | New from Marc Veldhoen on Mastodon: (news): There is concern the virus may become part of the circulating influenza viruses. It would be good to include H5N1 in the annual vaccines. But, this should be more broadly targeted. → https://mastodon.online/@marc_veld/113519904591419118 | 09:11 |
| Brainstorm | New from Marc Veldhoen on Mastodon: (translated) (**news): **Desinformatie Pot **verstrekkende series have. Think at man #this believe that they ##itself self 'autonomic' or '**soeverein' can announce, or #old #this ##itself self and their children from inoculation prevent. The outcome? **Vermijdbare Earnest illnesses [... want %more?] → https://mastodon.online/@marc_veld/113520325916768761 | 11:00 |
| Brainstorm | New from PubMed: Vanessa Pinho: Disruption of survivin protein expression by treatment with YM155 accelerates the resolution of neutrophilic inflammation → https://pubmed.ncbi.nlm.nih.gov/39568085/ | 11:10 |
| Brainstorm | New from PubMed: Vanessa Pinho: Disruption of survivin protein expression by treatment with YM155 accelerates the resolution of neutrophilic inflammation → https://pubmed.ncbi.nlm.nih.gov/39568085/ | 11:38 |
| Brainstorm | New from PubMed: Outcome of Acute Appendicitis During COVID-19 Infection: Acute appendicitis is the main cause of urgent abdominal surgeries performed worldwide. The disease is most prevalent in the second and third decades of life, and patients typically range in age from five to 45. One of the most common non-elective procedures [... want %more?] → https://pubmed.ncbi.nlm.nih.gov/39569304/ | 12:28 |
| Brainstorm | New from Marc Veldhoen on Mastodon: (news): This shows that the memory cells stored (referred to as imprinting) have improved via vaccination and infection, and have increased neutralisation activity to Omicron sublineages. However, do remember that antibodies will wane, and infections will take place. → https://mastodon.online/@marc_veld/113520752052527962 | 12:48 |
| Brainstorm | New from Marc Veldhoen on Mastodon: (news): Some older people will have difficulties maintaining their memory cells and antibodies may wane faster. This means it remains highly advisable to get the annual booster! Also this year, just like for the flu-vaccine: it is to protect you and those around you. It works! → https://mastodon.online/@marc_veld/113520915587509480 | 13:27 |
| Brainstorm | New from r/Science: science: Potential Single-Dose Smallpox and Mpox Vaccine Advances → https://old.reddit.com/r/science/comments/1gwg8vg/potential_singledose_smallpox_and_mpox_vaccine/ | 15:15 |
| Brainstorm | New from StatNews: Top FDA official says Trump and RFK Jr. will mean ‘vigorous dialogue’ on vaccines: The FDA's Peter Marks says Trump and RFK Jr. will give scientists the chance to make the case for the value of immunizations. → https://www.statnews.com/2024/11/21/peter-marks-fda-rfk-jr-vaccine-safety/ | 15:25 |
| Brainstorm | New from r/Coronavirus: Coronavirus: What you should know about COVID-19 for this holiday season → https://old.reddit.com/r/Coronavirus/comments/1gwhp0s/what_you_should_know_about_covid19_for_this/ | 15:45 |
| Brainstorm | New from Reddit (test): COVID19_Pandemic: Jammer: "…NBA players seem to be struggling with the same ‘mystery illness’ as millions of other Americans who can’t connect the dots." / "…One would think a league official or a journalist might be just a little [... want %more?] → https://old.reddit.com/r/COVID19_Pandemic/comments/1gwiryu/jammer_nba_players_seem_to_be_struggling_with_the/ | 17:25 |
| Brainstorm | New from BBC Health: NHS hours from PPE running out in Covid - Hancock: Former health secretary tells inquiry some healthcare settings did run out - "and it was awful". → https://www.bbc.com/news/articles/ce89k5j27z1o | 18:04 |
| Brainstorm | New from MedPageToday: FDA Approves Zanidatamab for Biliary Tract Cancer: (MedPage Today) -- The FDA on Wednesday granted accelerated approval to zanidatamab (Ziihera), a bispecific antibody, for pretreated HER2-positive biliary tract cancer.Approval stipulates use in unresectable or metastatic cases, [... want %more?] → https://www.medpagetoday.com/hematologyoncology/othercancers/113040 | 19:33 |
| Brainstorm | New from Marc Veldhoen on Mastodon: (news): The death rates in 2023 and 2024 seem substantially lower than pre-pandemic times, which seems to indicate a death deficit due to the high level of COVID-19 deaths in 2020-2021. All this, like SARS-CoV-2, the immune response and the epidemiology is according to our knowledge. → https://mastodon.online/@marc_veld/113522503231471278 | 20:12 |
| Brainstorm | New from StatNews: Pfizer’s new R&D head, a VC deep-dive, and a new FDA commissioner?: On STAT's podcast, hear about what’s in store for biotech VCs in 2025, Pfizer's new head of R&D, drug innovation in a second Trump term, and more. → https://www.statnews.com/2024/11/21/pfizer-biotech-2025-venture-capital-outlook-fda-commissioner-trump/ | 20:51 |
| Brainstorm | New from CIDRAP: Adults with migraines at higher risk of depression during pandemic, study shows: The cumulative incidence of depression was higher among those with migraine during the fall of 2020 (14.9%) than in those without migraine (11.8%). → https://www.cidrap.umn.edu/covid-19/adults-migraines-higher-risk-depression-during-pandemic-study-shows | 21:21 |
| Brainstorm | New from CIDRAP: (news): Antiviral COVID-19 drug molnupiravir tied to large drop in deaths in older patients → https://www.cidrap.umn.edu/covid-19/antiviral-covid-19-drug-molnupiravir-tied-large-drop-deaths-older-patients | 22:09 |
| LjL | de-facto, ↑ i think paxlovid had evidence of little effect on mortality lately? | 23:05 |
| Brainstorm | New from MedPageToday: Malaria Vaccine Delivered by Mosquito Bite Shows Safety, Efficacy: (MedPage Today) -- Immunization with a second-generation genetically attenuated parasite was safe and provided strong protection from malaria infection in young adults, a small clinical trial in the [... want %more?] → https://www.medpagetoday.com/infectiousdisease/generalinfectiousdisease/113051 | 23:27 |
| de-facto | LjL, i dont like the concept of "throwing a wrench into the gears of the biosynthesis engine of cells to create a mutation catastrophe" in general. Certainly it also causes that catastrophic accumulation of mutations on viral reproduction hence inhibit that in a generic enough way that evasion mutations are unrealistic for the virus. | 23:34 |
| LjL | yes man i know what you think of molnupiravir | 23:35 |
| de-facto | regardless its interesting to take a look at their data | 23:44 |
| de-facto | %title https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofae685/7904736 | 23:44 |
| Brainstorm | de-facto: From academic.oup.com: Real clinical effectiveness of molnupiravir against 30-day mortality among 74 541 SARS-CoV-2 positive patients: a nationwide cohort study from the Czech Republic | Open Forum Infectious Diseases | [...] | 23:44 |
| LjL | open access journal eh | 23:45 |
| Brainstorm | New from Marc Veldhoen on Mastodon: (news): vaccines rapidly recall the response against conserved epitopes (imprinting), which ensures the response to focus and to future-proof it. However, this does not prevent the recruitment of new B cells against new epitopes. → https://mastodon.online/@marc_veld/113523335476411634 | 23:46 |
| de-facto | how do they compensate for cofactors such as that patients that may refuse any treatment having a higher probability for mortality due to lack of necessary assistance/monitoring/etc and thereby also automatically being in the non-Molnupiravir group? | 23:49 |
| de-facto | at least vaccination status seems to be balanced between incident and control groups | 23:52 |
| de-facto | i mean if you really wanted to know you would have to do a double blinded study, e.g. hand both placebo and monupilnavir to the doctors treating patients and only unblind after the treatment ended, yet thats wont go through ethics committee | 23:55 |
Generated by irclog2html.py 2.17.0 by Marius Gedminas - find it at https://mg.pov.lt/irclog2html/!