libera/##covid-19/ Thursday, 2024-11-07

BrainstormNew from ##covid-19 Zotero group: Deficient Generation of Spike-Specific Long-Lived Plasma Cells in the Bone Marrow After Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Item Type Journal Article Author Zahra R Tehrani Author Parham Habibzadeh Author Robin Flinko Author Hegang Chen Author Abdolrahim Abbasi [... want %more?] → https://www.zotero.org/groups/covid_links/items/69RM2NFI00:34
BrainstormNew from ##covid-19 Zotero group: SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination: Item Type Journal Article Author Doan C. Nguyen Author Ian T. Hentenaar Author Andrea Morrison-Porter Author David Solano Author Natalie S. Haddad Author [... want %more?] → https://www.zotero.org/groups/covid_links/items/DDBMRALG00:44
BrainstormNew from r/COVID19: COVID19: Immunologic and Biophysical Features of the BNT162b2 JN.1- and KP.2-Adapted COVID-19 Vaccines → https://old.reddit.com/r/COVID19/comments/1glldu7/immunologic_and_biophysical_features_of_the/08:59
BrainstormNew from r/Science: science: Maternal antibodies passed across the placenta can interfere with the response to the malaria vaccine, which would explain its lower efficacy in infants under five months of age, according to new research. → https://old.reddit.com/r/science/comments/1gllqem/maternal_antibodies_passed_across_the_placenta/10:46
BrainstormNew from Marc Veldhoen on Mastodon: (news): The claim "if you are not sick, you should not be required to take a product" misses two points. There is no obligation, and vaccines are preventative products. They work by keeping you healthy and are given to you when you are healthy. If already ill, they will not work! → https://mastodon.online/@marc_veld/11344121740961673711:35
BrainstormNew from Marc Veldhoen on Mastodon: (news): Causing doubts, with wrong information and tropes, reduces vaccine uptake. This will reduce protection for all, the non-vaccinated, the siblings, and those with a weaker system. The latter also includes adults, especially the elderly. Collectively, this allows the return of → https://mastodon.online/@marc_veld/11344125295714775111:45
BrainstormNew from PubMed: Target antigen screening and development of a multi-component subunit vaccine against Mycoplasma synoviae in chickens: INTRODUCTION: Mycoplasma synoviae (MS) is a globally important avian pathogen causing infectious synovitis and respiratory diseases in poultry, leading to significant economic losses. Despite [... want %more?] → https://pubmed.ncbi.nlm.nih.gov/39507944/12:24
BrainstormNew from BMJ: The rapid rise of the UK’s cancer vaccine trials: The UK is on its way to becoming a hotbed of cancer vaccine trials. In May this year,1 it emerged that 30 British hospitals had signed up to be part of the Cancer Vaccine Launch Pad,2 a scheme to enrol NHS patients in messenger RNA (mRNA) cancer vaccine trials. [... want %more?] → http://www.bmj.com/content/387/bmj.q2294.short14:00
BrainstormNew from Marc Veldhoen on Mastodon: (news): On average, there is an increase from base line, for the risk of an autoimmune disease. Do not interpret that SARS-CoV-2 gives you autoimmunity, it is the inflammatory response against any infection that enhances this. This is somewhat higher in the absence of immune memory. → https://mastodon.online/@marc_veld/11344193717620578914:40
BrainstormNew from EMA: What's new: (news): Human medicines European public assessment report (EPAR): M-M-RVaxPro, measles, mumps and rubella vaccine (live), Date of authorisation: 05/05/2006, Revision: 32, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/m-m-rvaxpro15:10
BrainstormNew from Reddit (test): COVID19_Pandemic: What It’s Like to Have Long COVID As a Kid → https://old.reddit.com/r/COVID19_Pandemic/comments/1glr9d3/what_its_like_to_have_long_covid_as_a_kid/15:20
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: We’re reading about RFK Jr. looking to shrink the FDA, an AstraZeneca exec held in China, and more → https://www.statnews.com/pharmalot/2024/11/07/fda-kennedy-sarepta-duchenne-astrazeneca-china-novavax-covid-california-340b/15:30
BrainstormNew from StatNews: D.C. Diagnosis: RFK Jr. targets the F in FDA: Yesterday, RFK Jr. suggested he’d fire officials in the FDA’s food division, but said he wouldn’t pull vaccines off the market. Here's what we know so far about RFK Jr.'s… → https://www.statnews.com/2024/11/07/election-healthcare-news-maha-abortion-policy-fda-rfk-jr-dc-diagnosis/15:51
BrainstormNew from EMA: What's new: (news): Veterinary medicines European public assessment report (EPAR): Canigen L4, Canine leptospirosis vaccine (inactivated), Status: Authorised → https://www.ema.europa.eu/en/medicines/veterinary/EPAR/canigen-l416:01
BrainstormNew from BMJ Open: Effects of paravertebral block on postoperative analgesia in children undergoing unilateral thoracotomy cardiac surgery with cardiopulmonary bypass: protocol for a randomised controlled trial: Introduction This study aims to determine whether paravertebral block (PVB) provides better postoperative [... want %more?] → http://bmjopen.bmj.com/cgi/content/short/14/11/e08646217:31
BrainstormNew from r/COVID19: COVID19: Effect of COVID-19 vaccination on the risk of developing post-COVID conditions: The VENUS study → https://old.reddit.com/r/COVID19/comments/1gluno0/effect_of_covid19_vaccination_on_the_risk_of/17:42
BrainstormNew from Marc Veldhoen on Mastodon: (news): The analysis is mainly performed on female subjects. The groups assessed only vaccinated individuals,  with status distant (1 year), intermediate (6Mo- 1Y), or recent vaccination (14-149 days). → https://mastodon.online/@marc_veld/11344284680142098218:31
BrainstormNew from BBC Health: Covid inquiry told top NHS doctor was terrified: Sir Stephen Powis says points-based tool was drawn up should need to prioritise patients have arisen. → https://www.bbc.com/news/articles/cd0gdzdv53yo18:51
BrainstormNew from New Scientist: Bird flu antibodies found in dairy workers in Michigan and Colorado: Blood tests have shown that about 7 per cent of workers on dairy farms that had H5N1 outbreaks had antibodies against the disease → https://www.newscientist.com/article/2455411-bird-flu-antibodies-found-in-dairy-workers-in-michigan-and-colorado/19:30
ublxcan't tell if that's scary or not scary19:45
LjLublx, the bird flu thing?20:25
LjL> They found H5N1 antibodies in eight of the samples, or about 7 per cent, suggesting that eight of the workers had been unknowingly infected with the virus. What’s more, four of the workers didn’t recall ever having symptoms.20:26
LjLpretty small sample eh20:26
LjLalso 50% symptoms is better than 100% symptoms i guess but still substantial (depending on the symptoms)20:27
LjLi'd like a study like this being done with random individuals in the population20:27
ublx50% symptoms not terribly dramatic is better than dramatic symptoms, although i suppose that picture could change if it breaks out more widely20:29
ublxhmm, well: "H5N1 is poorly adapted to infecting humans and isn’t known to transmit between people. Still, more than 900 people globally are reported to have had the virus since 2003, roughly half of whom died from it."20:31
LjLublx, yeah in general it's been reported as very deadly but there could be all kinds of biases like maybe a lot of people have had it and were never tested20:36
LjLalso maybe the virus as coming from cattle is not quite the one you'll find in dinosaurs20:36
LjLi think the thing that's feared the most is recombination of the cattle virus with this year's regular human flu20:37
LjLhigh fatality + high h2h transmissibility20:37
ublxas a recent flu recoveree..20:37
* ublx shudders20:37
LjLublx, i'm getting my jabs tomorrow20:44
LjLif i wake up in time20:44
ublxdrive to the jab clinic now then sleep in the car!20:45
LjLdefinitely not driving anywhere20:47
BrainstormNew from r/COVID19: COVID19: COVID-19 pandemic interventions reshaped the global dispersal of seasonal influenza viruses → https://old.reddit.com/r/COVID19/comments/1glz7ig/covid19_pandemic_interventions_reshaped_the/20:48
BrainstormNew from CIDRAP: Research shows nasal swab could help predict COVID-19 severity: Nasal autoantibodies likely latched on to viral molecules, preventing excessive inflammation. → https://www.cidrap.umn.edu/covid-19/research-shows-nasal-swab-could-help-predict-covid-19-severity21:28
BrainstormNew from Eric Topol on Mastodon: (news): The Covid pandemic suppressed Flu. A new study investigated why → https://mstdn.social/@erictopol/11344360667153858821:48
BrainstormNew from CIDRAP: (news): Trial shows safety of getting COVID, flu vaccines at same time → https://www.cidrap.umn.edu/covid-19/trial-shows-safety-getting-covid-flu-vaccines-same-time22:07
LjLwell that's a relief since i'm getting both of those tomorrow! :P23:06

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