| Brainstorm | New from The Lancet (Online): [Correspondence] The opioid crisis in Nigeria: a call for public health and policy interventions: The opioid crisis, once primarily a concern of high-income countries, is increasingly becoming a substantial public health challenge in Nigeria.1 The alarming rise [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)01855-5/fulltext | 00:32 |
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| Brainstorm | New from r/Science: science: Swedish scientists document the origin of a recombinant variant of SARS-CoV-2 for the first time. They report how a patient infected with two different variants directly transmitted a novel hybrid to another person in the hospital. → https://old.reddit.com/r/science/comments/1fu6b8q/swedish_scientists_document_the_origin_of_a/ | 05:21 |
| Brainstorm | New from r/WorldNews: worldnews: Palestinian officials say 32 killed in Israeli strikes on southern Gaza → https://old.reddit.com/r/worldnews/comments/1fua38q/palestinian_officials_say_32_killed_in_israeli/ | 09:12 |
| Brainstorm | New from r/COVID19: COVID19: Eight-Week Creatine-Glucose Supplementation Alleviates Clinical Features of Long COVID → https://old.reddit.com/r/COVID19/comments/1fuawi1/eightweek_creatineglucose_supplementation/ | 10:02 |
| Brainstorm | New from ProPublica: A Pair of Billionaire Preachers Built the Most Powerful Political Machine in Texas. That’s Just the Start.: by Ava Kofman ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon [... want %more?] → https://www.propublica.org/article/tim-dunn-farris-wilks-texas-christian-nationalism-dominionism-elections-voting | 11:48 |
| Brainstorm | New from PubMed: Field efficacy of a recombinant toxoid vaccine against Shiga toxin 2e during a naturally occurring edema disease infection: The objective of this field trial was to determine the efficacy of a recombinant toxoid vaccine against Shiga toxin 2e (Stx2e) in piglets suffering from edema disease (ED). Three farms with [... want %more?] → https://pubmed.ncbi.nlm.nih.gov/39355683/ | 13:06 |
| Brainstorm | New from BMJ Open: Impact of community-based multidomain preventive health program on healthcare utilisation among elderly persons in Singapore: a propensity score matched and difference-in-differences study: Objectives Ageing populations present substantial challenges for healthcare systems. Community-based health [... want %more?] → http://bmjopen.bmj.com/cgi/content/short/14/10/e086327 | 13:45 |
| Brainstorm | New from Marc Veldhoen on Mastodon: (news): Immunologically, the new mutations may combine immune evasion strategies, such as less neutralising antibodies binding, with receptor binding properties or additional immune altering properties. However, it will not escape immunity: for that many large changes would be needed → https://mastodon.online/@marc_veld/113237680145569154 | 13:55 |
| Brainstorm | New from Contagion Live: Shifting Patterns of Staphylococcus aureus Infections in Pediatric Patients: This study revealed a significant decline in MSSA and a corresponding rise MRSA, particularly linked to COVID-19 social isolation measures. → https://www.contagionlive.com/view/shifting-patterns-of-staphylococcus-aureus-infections-in-pediatric-patients | 14:25 |
| Brainstorm | New from Reddit (test): COVID19_Pandemic: Potential cluster of H5N1 bird flu cases in Missouri poses danger of human-to-human transmission → https://old.reddit.com/r/COVID19_Pandemic/comments/1fufoo3/potential_cluster_of_h5n1_bird_flu_cases_in/ | 15:14 |
| Brainstorm | New from Reddit (test): COVID19_Pandemic: Two new studies on mucosal vaccines and Long COVID underscore the criminality of the “forever COVID” policy → https://old.reddit.com/r/COVID19_Pandemic/comments/1fufq0y/two_new_studies_on_mucosal_vaccines_and_long/ | 15:54 |
| Brainstorm | New from r/Coronavirus: Coronavirus: For COVID ‘long haulers,’ glimmers of good news → https://old.reddit.com/r/Coronavirus/comments/1fuh38l/for_covid_long_haulers_glimmers_of_good_news/ | 16:14 |
| Brainstorm | New from r/WorldNews: worldnews: Russia plans emergency public warning tests on Wednesday → https://old.reddit.com/r/worldnews/comments/1fuh9qf/russia_plans_emergency_public_warning_tests_on/ | 16:44 |
| Brainstorm | New from r/Coronavirus: Coronavirus: Arizona prisoners: Inmates were given do-not-resuscitate status against their will during COVID-19 → https://old.reddit.com/r/Coronavirus/comments/1fui1uv/arizona_prisoners_inmates_were_given/ | 16:55 |
| Timvde | I can apparently still get a free COVID vaccine. It's based on the JN.1 variant apparently. I'm totally not up-to-date with variants. Is it sensible to take it? | 20:26 |
| LjL | Timvde: the most recent vaccine is based on KP.2, which is more recent than JN.1, but the EU has apparently decided to use a mixture. The actual circulating variants are even more recent though, with KP.3 already being replaced by some subvariant or recombinant or I don't even know. | 20:34 |
| LjL | I think I will personally try to get a KP.2 vaccine over JN.1 even if that might mean delaying it a little, but that's not really based on knowing which of them is better targeted to actual current variants | 20:35 |
| LjL | Timvde: also I'm not sure if I understood things correctly, but I think Novavax may be JN.1 while the mRNA vaccines may be KP.2 (not necessarily in general, just what's around in the EU now, or possibly just in Italy in which case it doesn't matter), but if you have a preference wrt mRNA or not, then just consider it may be tied to whether it's KP.2 or JN.1 | 20:36 |
| Timvde | The federal website just says it's JN.1 | 20:37 |
| Timvde | Comirnaty, so that's Moderna iirc | 20:37 |
| Timvde | Or is it Pfizer? Damn, I don't even remember. | 20:37 |
| Timvde | It's Pfizer | 20:37 |
| LjL | Pfizer | 20:38 |
| LjL | Then I guess disregard last message | 20:39 |
| Timvde | I think the JP.2 vaccines aren't approved by the EMA yet: https://www.ema.europa.eu/en/human-regulatory-overview/public-health-threats/coronavirus-disease-covid-19/covid-19-medicines | 20:39 |
| Timvde | KP.2* | 20:40 |
| LjL | Then maybe disregard everything I've said ;( | 20:40 |
| LjL | Timvde: good thing the updated vaccine was ready and being considered back in June already... https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-receive-positive-chmp-opinion-omicron-4 | 20:42 |
| Brainstorm | New from CIDRAP: (news): Lithium aspartate didn't relieve long-COVID fatigue, brain fog in trial participants → https://www.cidrap.umn.edu/covid-19/lithium-aspartate-didnt-relieve-long-covid-fatigue-brain-fog-trial-participants | 21:01 |
| LjL | Timvde: [20:52] superkuh: KP.* are directly downstream JN.1. Novavax's choice to go JN.1 again this year seems well supported enough. I don't think it matters much | 21:16 |
| Timvde | Where's that from? | 21:16 |
| LjL | ##coronavirus | 21:18 |
| Timvde | Oh, I think I misread the press release you linked | 21:18 |
| Timvde | > Data demonstrate that the Omicron KP.2-adapted COVID-19 vaccine generates a substantially improved response against multiple circulating Omicron JN.1 sublineages as did the Omicron JN.1-adapted COVID-19 vaccine authorized by the European Commission (EC) in July 2024 | 21:18 |
| Timvde | "as did" != "as compared to" | 21:18 |
| Brainstorm | New from r/Science: science: Southern Californians are chronically being exposed to toxic airborne plastic chemicals called plasticizers, chemicals that make materials more flexible, used in lunchboxes, shower curtains, garden hoses and upholstery. The phthalates in the air are [... want %more?] → https://old.reddit.com/r/science/comments/1fuo7ji/southern_californians_are_chronically_being/ | 21:20 |
| LjL | Timvde: yes that's how I read it. Then again what would the vaccine maker claim | 21:23 |
| LjL | Also the press release was put out before the current whareveritis variant started rising. I'm not sure if KP.3 and descendants are itself a sublineage of KP.2 or they go back to JN.1 (plus any recombination?) | 21:24 |
| LjL | With the confusion I feel nowadays I don't really know how I used to successfully follow this stuff before | 21:25 |
| LjL | Maybe I never did and just thought I did | 21:25 |
| LjL | superkuh is generally clueful, anyway | 21:26 |
| Brainstorm | New from MedPageToday: Low-Dose Lithium Tested in Long COVID: (MedPage Today) -- Low doses of lithium aspartate did not successfully treat neurologic symptoms of long COVID, a randomized, double-blind, placebo-controlled trial showed.In a study of 52 people with long COVID, lithium aspartate at 10 to 15... → https://www.medpagetoday.com/neurology/longcovid/112226 | 22:18 |
| Brainstorm | New from MedPageToday: Can HPV Self-Tests Truly Replace Pap Smears?: (MedPage Today) -- Back in May of this year, the FDA approved a new method of human papillomavirus (HPV) testing in a healthcare setting. Rather than a standard Pap smear performed with a speculum -- a test dreaded by many patients -- the new... → https://www.medpagetoday.com/obgyn/cervicalcancer/112231 | 23:16 |
| Brainstorm | New from Marc Veldhoen on Mastodon: (news): In vitro attempts to infect these T cells showed that SARS-CoV-2 viral particles do not infect MAIT cells. The virus also does not directly activate these cells, this is likely indirect via cytokines and metabolites produced during the inflammatory response. → https://mastodon.online/@marc_veld/113239978392844650 | 23:45 |
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