libera/##covid-19/ Saturday, 2024-06-15

BrainstormNew from MedPageToday: SGLT2 Inhibitor No Help for ICU Patients With Acute Organ Dysfunction: (MedPage Today) -- Adding an SGLT2 inhibitor to standard care did not improve clinical outcomes in critically ill patients with acute organ dysfunction, an open-label randomized trial involving intensive care [... want %more?] → https://www.medpagetoday.com/criticalcare/generalcriticalcare/11066900:22
BrainstormNew from The Lancet: [World Report] African vaccine manufacturing scheme to boost production: Gavi is launching the African Vaccine Manufacturing Accelerator to promote domestic vaccine production. Udani Samarasekera reports. → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)01239-X/fulltext01:27
LjL%title https://www.ineteconomics.org/perspectives/blog/debilitating-a-generation-expert-warns-that-long-covid-may-eventually-affect-most-americans courtesy of the other channel, hi ublx03:40
BrainstormLjL: From www.ineteconomics.org: “Debilitating a Generation”: Expert Warns That Long COVID May Eventually Affect Most Americans | Institute for New Economic Thinking03:40
ublxthis is going to be the most cheerful thing i read today isn't it04:41
LjLublx, nah04:50
LjLthe most cheerful will be04:50
LjL> kawaoka stated that “if h7n9 viruses acquire the ability to transmit efficiently from person to person, a worldwide outbreak is almost certain since humans lack protective immune responses to these types of viruses.”[21]04:50
LjL(50ish% mortality of course)04:50
ublx*bunker digging intensifies*04:51
ublxis 50% against a healthy host?04:53
ublxor 50% against a host who has had covid half a dozen times?04:53
LjL> Since the first human case in 2013, H7N9 avian influenza viruses (AIVs) have caused more than 1500 human infections with a mortality rate of approximately 40%.04:55
ublxwhat kind of occupations/living arrangements bring people into contact with H7N9?04:56
ublx"Chinese scientists announced the development of a vaccine on October 26, 2013, but said that H7N9 had not spread far enough to merit widespread vaccination." (wikipedia)04:59
ublx^ hey that's somewhat hopeful04:59
LjLublx, sure, i mean if it's been around since 2013 and we aren't all dead yet... it's just a scary prospect that we have no meaningful immune response to it and that 1500 people did get infected so it's not a wholly theoretical concern05:00
LjLstill, the practical concern right now is obviously H5N105:00
BrainstormNew from ##covid-19 Zotero group: Opinion | Why the Pandemic Probably Started in a Lab, in 5 Key Points: Item Type Newspaper Article Author Alina Chan URL https://www.nytimes.com/interactive/2024/06/03/opinion/covid-lab-leak.html Publication The New York Times ISSN 0362-4331 Date 2024-06-03 Section Opinion Accessed [... want %more?] → https://www.zotero.org/groups/covid_links/items/DU854J7S05:27
BrainstormNew from This Week In Virology: TWiV 1122: Clinical update with Dr. Daniel Griffin: In his weekly clinical update, Dr. Griffin discusses expanded use of the RSV vaccine by GSK, how the youngest member of the MicrobeTV family was hospitalized with RSV, why we are seeing more RSV infections than before the pandemic and how [... want %more?] → https://www.microbe.tv/twiv/twiv-1122/06:16
BrainstormNew from Retraction Watch: Weekend reads: ‘An epidemic of scientific fakery’; death threats for critics; Cleveland Clinic settles mismanagement allegations for $7.6 million: Would [... want %more?] → https://retractionwatch.com/2024/06/15/weekend-reads-an-epidemic-of-scientific-fakery-death-threats-for-critics-cleveland-clinic-settles-mismanagement-allegations-for-7-6-million/12:06
BrainstormNew from StatNews: First Opinion: Opinion: Readers respond to a plea for rare disease progress, vaccine-related injury, and more → https://www.statnews.com/2024/06/15/letters-editor-first-opinion-rare-disease-progress-vaccine-related-injury-more/13:03
BrainstormNew from Marc Veldhoen on Mastodon: (news): The COVID-19 Nursing Home Data clearly shows that COVID vaccines worked! → https://mastodon.online/@marc_veld/11262042146658082813:41
BrainstormNew from r/COVID19: COVID19: Duration of Symptoms and Association With Positive Home Rapid Antigen Test Results After Infection With SARS-CoV-2 → https://old.reddit.com/r/COVID19/comments/1dggjkg/duration_of_symptoms_and_association_with/14:10
BrainstormNew from r/Coronavirus: Coronavirus: Yes, Everyone Really Is Sick a Lot More Often After Covid → https://old.reddit.com/r/Coronavirus/comments/1dgh1zj/yes_everyone_really_is_sick_a_lot_more_often/14:48
BrainstormNew from r/Science: science: Results from a new trial is the first time that consistent and durable responses to immunotherapy have been reported in difficult-to-treat metastatic colorectal or bowel cancer patients. The monoclonal antibodies work by triggering the body’s [... want %more?] → https://old.reddit.com/r/science/comments/1dghiql/results_from_a_new_trial_is_the_first_time_that/15:16
BrainstormNew from Reddit (test): COVID19_Pandemic: What causes long COVID? Case builds for rogue antibodies → https://old.reddit.com/r/COVID19_Pandemic/comments/1dghkzi/what_causes_long_covid_case_builds_for_rogue/16:13
BrainstormNew from Reddit (test): COVID19_Pandemic: More U.S. hospitals than ever require staff to get flu shots: 96% of hospitals serving veterans and 74% of hospitals serving the general public now require staff to get vaccinated against influenza or seek an exemption. → https://old.reddit.com/r/COVID19_Pandemic/comments/1dgikxu/more_us_hospitals_than_ever_require_staff_to_get/16:42
BrainstormNew from r/Science: science: Ultrasensitive liquid biopsy tech spots cancer earlier than standard methods: researchers showed that they could train a machine learning model to detect circulating tumor DNA (ctDNA) based on DNA sequencing data from patient blood tests, with very [... want %more?] → https://old.reddit.com/r/science/comments/1dgkk5z/ultrasensitive_liquid_biopsy_tech_spots_cancer/17:49
BrainstormNew from Reddit (test): COVID19_Pandemic: “Debilitating a Generation”: Expert Warns That Long COVID May Eventually Affect Most Americans → https://old.reddit.com/r/COVID19_Pandemic/comments/1dglgtg/debilitating_a_generation_expert_warns_that_long/18:37
BrainstormNew from Marc Veldhoen on Mastodon: (news): CD19 CAR-T cell therapy showed tolerable short-term safety in 2 MS patients, their expansion was observed in cerebrospinal fluid without neurotoxicity. Importantly, intrathecal antibody production decreased after CAR-T cell infusion in one patient. → https://mastodon.online/@marc_veld/11262180364666596219:34
BrainstormNew from Marc Veldhoen on Mastodon: (news): Climate change, rising social inequality and wrung-out healthcare services are contributing in ways that are hard to measure. The immune gap played a minor contribution in 2022-2023, a decrease in vaccination is another. → https://mastodon.online/@marc_veld/11262203307016710320:32

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